The MTHFR Gene: Why Your Vitamins Might Be Useless & What to Do About It
🚀 Upgrade Your Health with the Right Multivitamin
When I first started my biohacking journey, I was taking vitamins just to take them—assuming a daily multivitamin would cover all my nutritional bases. But after doing comprehensive bloodwork, I realized I wasn’t absorbing key nutrients properly.
Like most people, I thought all vitamins were the same, but after listening to Gary Brecka, Ben Greenfield, and Andrew Huberman, I learned that not all vitamins work for everyone—and for some people, they might not work at all.
One of the biggest game-changers I discovered? The MTHFR gene mutation. If you’ve been taking folic acid, thinking it’s helping your body, you might be wrong.
The solution? A methylated multivitamin that your body can actually use.
🔥 Top Recommended Methylated Multivitamins:
✔️ Pure Encapsulations O.N.E. – Best for daily energy & antioxidant support
✔️ PureGenomics Multivitamin – Best for those with MTHFR mutations
✔️ Thorne Basic Nutrients 2/Day – Well-rounded, high-absorption formula
🔗 Click here to order now and start feeling your best!
What is the MTHFR Gene?
The MTHFR gene helps your body convert folic acid into its active form, methylfolate (5-MTHF). This process, called methylation, happens 300 billion times a day in your body.
🔴 The Problem: Up to 40% of people have an MTHFR mutation, making it difficult to process folic acid properly.
✅ The Solution: Switching to a methylated multivitamin ensures your body absorbs nutrients correctly.
As Gary Brecka explains:
“The most important process that human beings go through 300 billion times a day is a process called methylation. The MTHFR gene mutation affects this process by preventing folate and synthetic folic acid from converting into the active form your body needs.”
High-Level Breakdown: Which Multivitamin is Right for You?
| Feature | Pure Encapsulations O.N.E. | PureGenomics Multivitamin | Thorne Basic Nutrients 2/Day |
|---|---|---|---|
| Best For | Daily energy, antioxidants | MTHFR mutation, brain & heart health | Overall wellness & absorption |
| Methylated B Vitamins | ✅ Yes | ✅ Yes | ✅ Yes |
| B12 Type | Methylcobalamin & Adenosylcobalamin | Methylcobalamin | Methylcobalamin |
| B9 (Folate) Type | L-5-MTHF | L-5-MTHF | L-5-MTHF |
| Antioxidants | CoQ10, Lutein, Zeaxanthin | No added antioxidants | No added antioxidants |
| Iron-Free? | ✅ Yes | ✅ Yes | ✅ Yes |
| Extra Nutrients | NAC, Alpha Lipoic Acid | Choline & Inositol | Magnesium, Zinc, Selenium |
💡 Need help choosing?
- Pick O.N.E. if you want a daily boost with antioxidants
- Pick PureGenomics if you have MTHFR gene concerns
- Pick Thorne 2/Day if you need a balanced, well-absorbed formula
👉 Order Now & Optimize Your Health
What to Do If You Have an MTHFR Mutation
1️⃣ Switch to a Methylated Multivitamin
Since your body struggles to process folic acid, the best solution is a methylated multivitamin with:
✅ Methylfolate (5-MTHF) – Instead of folic acid
✅ Methylcobalamin (B12) – Instead of cyanocobalamin
✅ P5P (B6) – Instead of pyridoxine HCl
✅ Riboflavin-5-Phosphate (B2) – Instead of standard riboflavin
🔹 Best Methylated Multivitamins:
- Pure Encapsulations O.N.E. – Great for overall health & energy
- PureGenomics Multivitamin – Designed for MTHFR support
- Thorne Basic Nutrients 2/Day – Well-rounded, high-absorption formula
2️⃣ Support Methylation with the Right Nutrients
In addition to a methylated multivitamin, you can improve methylation with:
✅ Choline & Inositol – Supports brain function and neurotransmitter production
✅ Trimethylglycine (TMG) – Helps lower high homocysteine
✅ Magnesium – Helps activate B vitamins and supports detox
✅ NAC (N-Acetyl Cysteine) – Boosts glutathione, your body’s master antioxidant
3️⃣ Avoid Folic Acid & Processed Foods
Since your body can’t process folic acid properly, it’s best to avoid synthetic folic acid found in:
🚫 Fortified cereals and grains
🚫 Processed breads and pasta
🚫 Cheap, non-methylated multivitamins
Instead, focus on natural folate sources, like:
🥑 Avocados
🥬 Leafy greens (spinach, kale)
🍊 Citrus fruits
🍗 Grass-fed liver
Final Thoughts: Optimize Your Health Today
If you’ve been taking vitamins but still feel tired, foggy, or anxious, your MTHFR gene could be the reason. Switching to a methylated multivitamin can help your body absorb nutrients better and optimize energy, brain function, and long-term health.
🔗 Get the Best Methylated Multivitamin for You:
✔️ Pure Encapsulations O.N.E. – Daily Energy & Antioxidants
✔️ PureGenomics – MTHFR Support & Brain Health
✔️ Thorne 2/Day – Balanced & Highly Absorbable
🚀 Order now and take control of your health!
Affiliate Disclosure
As an Amazon Associate, I earn from qualifying purchases. This comes at no extra cost to you and helps support this blog.
Next Steps: More Biohacking Insights Coming Soon
This is just the beginning! Over the next few posts, I’ll be diving into:
🔥 How to optimize detoxification with glutathione & liver support
🔥 The truth about homocysteine & heart disease
🔥 How to stack methylation-boosting supplements for peak performance
Stay tuned—and let’s optimize your health together! 🚀